Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling

Identifying the target of an antiparasitic compound in Toxoplasma using thermal proteome profiling

Copyright © 2020 American Chemical Society. Apicomplexan parasites include the causative agents of malaria and toxoplasmosis. Cell-based screens in Toxoplasma previously identified a chemical modulator of calcium signaling (ENH1) that blocked parasite egress from host cells and exhibited potent anti...

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Bibliographic Details
Main Authors: Herneisen, Alice L, Sidik, Saima M, Markus, Benedikt M, Drewry, David H, Zuercher, William J, Lourido, Sebastian
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Chemical Society (ACS) 2021
Online Access:https://hdl.handle.net/1721.1/135498

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