Development of a platform process for the production and purification of single‐domain antibodies

Development of a platform process for the production and purification of single‐domain antibodies

Single-domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform manufacturing process. While successful production of a variety of sdAbs has be...

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Bibliographic Details
Main Authors: Crowell, Laura E, Goodwine, Chaz, Holt, Carla S, Rocha, Lucia, Vega, Celina, Rodriguez, Sergio A, Dalvie, Neil C, Tracey, Mary K, Puntel, Mariana, Wigdorovitz, Andrés, Parreño, Viviana, Love, Kerry R, Cramer, Steven M, Love, J Christopher
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Wiley 2021
Online Access:https://hdl.handle.net/1721.1/135524

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