A brief review of genome editing technology for generating animal models

© The Author(s) 2020. The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animal models. This mini-review briefly summarizes the development of major genome editin...

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Main Authors: WANG, Haoyi, WU, Sen, CAPECCHI, Mario R, JAENISCH, Rudolf
Format: Article
Language:English
Published: Editorial Department of Engineering Sciences 2021
Online Access:https://hdl.handle.net/1721.1/135543
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author WANG, Haoyi
WU, Sen
CAPECCHI, Mario R
JAENISCH, Rudolf
author_facet WANG, Haoyi
WU, Sen
CAPECCHI, Mario R
JAENISCH, Rudolf
author_sort WANG, Haoyi
collection MIT
description © The Author(s) 2020. The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animal models. This mini-review briefly summarizes the development of major genome editing tools, focusing on the application of these tools to generate animal models in multiple species.
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spelling mit-1721.1/1355432021-10-28T05:01:44Z A brief review of genome editing technology for generating animal models WANG, Haoyi WU, Sen CAPECCHI, Mario R JAENISCH, Rudolf © The Author(s) 2020. The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animal models. This mini-review briefly summarizes the development of major genome editing tools, focusing on the application of these tools to generate animal models in multiple species. 2021-10-27T20:23:56Z 2021-10-27T20:23:56Z 2020 2021-07-19T17:16:59Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/135543 en 10.15302/J-FASE-2019309 Frontiers of Agricultural Science and Engineering Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Editorial Department of Engineering Sciences Frontiers
spellingShingle WANG, Haoyi
WU, Sen
CAPECCHI, Mario R
JAENISCH, Rudolf
A brief review of genome editing technology for generating animal models
title A brief review of genome editing technology for generating animal models
title_full A brief review of genome editing technology for generating animal models
title_fullStr A brief review of genome editing technology for generating animal models
title_full_unstemmed A brief review of genome editing technology for generating animal models
title_short A brief review of genome editing technology for generating animal models
title_sort brief review of genome editing technology for generating animal models
url https://hdl.handle.net/1721.1/135543
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