Tunable protein crystal size distribution via continuous slug-flow crystallization with spatially varying temperature

<jats:p>Under appropriate buffer and pH conditions, the magnitude and dispersion of the product protein crystals were reproducibly manipulated by controlling the spatial temperature along the tube in a continuous tubular crystallizer.</jats:p>

Bibliographic Details
Main Authors: Mozdzierz, Nicholas J, Hong, Moo Sun, Lee, Yongkyu, Benisch, Moritz HP, Jiang, Mo, Myerson, Allan S, Braatz, Richard D
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC) 2021
Online Access:https://hdl.handle.net/1721.1/135587
Description
Summary:<jats:p>Under appropriate buffer and pH conditions, the magnitude and dispersion of the product protein crystals were reproducibly manipulated by controlling the spatial temperature along the tube in a continuous tubular crystallizer.</jats:p>