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author Baig, Hasan
Fontanarossa, Pedro
Kulkarni, Vishwesh
McLaughlin, James
Vaidyanathan, Prashant
Bartley, Bryan
Bhakta, Shyam
Bhatia, Swapnil
Bissell, Mike
Clancy, Kevin
Cox, Robert Sidney
Goñi Moreno, Angel
Gorochowski, Thomas
Grunberg, Raik
Lee, Jihwan
Luna, Augustin
Madsen, Curtis
Misirli, Goksel
Nguyen, Tramy
Le Novere, Nicolas
Palchick, Zachary
Pocock, Matthew
Roehner, Nicholas
Sauro, Herbert
Scott-Brown, James
Sexton, John T.
Stan, Guy-Bart
Tabor, Jeffrey J.
Terry, Logan
Vazquez Vilar, Marta
Voigt, Christopher A.
Wipat, Anil
Zong, David
Zundel, Zach
Beal, Jacob
Myers, Chris
author2 Massachusetts Institute of Technology. Department of Biological Engineering
author_facet Massachusetts Institute of Technology. Department of Biological Engineering
Baig, Hasan
Fontanarossa, Pedro
Kulkarni, Vishwesh
McLaughlin, James
Vaidyanathan, Prashant
Bartley, Bryan
Bhakta, Shyam
Bhatia, Swapnil
Bissell, Mike
Clancy, Kevin
Cox, Robert Sidney
Goñi Moreno, Angel
Gorochowski, Thomas
Grunberg, Raik
Lee, Jihwan
Luna, Augustin
Madsen, Curtis
Misirli, Goksel
Nguyen, Tramy
Le Novere, Nicolas
Palchick, Zachary
Pocock, Matthew
Roehner, Nicholas
Sauro, Herbert
Scott-Brown, James
Sexton, John T.
Stan, Guy-Bart
Tabor, Jeffrey J.
Terry, Logan
Vazquez Vilar, Marta
Voigt, Christopher A.
Wipat, Anil
Zong, David
Zundel, Zach
Beal, Jacob
Myers, Chris
author_sort Baig, Hasan
collection MIT
description <jats:title>Abstract</jats:title> <jats:p>People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.3 of SBOL Visual, which builds on the prior SBOL Visual 2.2 in several ways. First, the specification now includes higher-level “interactions with interactions,” such as an inducer molecule stimulating a repression interaction. Second, binding with a nucleic acid backbone can be shown by overlapping glyphs, as with other molecular complexes. Finally, a new “unspecified interaction” glyph is added for visualizing interactions whose nature is unknown, the “insulator” glyph is deprecated in favor of a new “inert DNA spacer” glyph, and the polypeptide region glyph is recommended for showing 2A sequences.</jats:p>
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spelling mit-1721.1/135615.22021-11-10T21:15:26Z Synthetic biology open language visual (SBOL Visual) version 2.3 Baig, Hasan Fontanarossa, Pedro Kulkarni, Vishwesh McLaughlin, James Vaidyanathan, Prashant Bartley, Bryan Bhakta, Shyam Bhatia, Swapnil Bissell, Mike Clancy, Kevin Cox, Robert Sidney Goñi Moreno, Angel Gorochowski, Thomas Grunberg, Raik Lee, Jihwan Luna, Augustin Madsen, Curtis Misirli, Goksel Nguyen, Tramy Le Novere, Nicolas Palchick, Zachary Pocock, Matthew Roehner, Nicholas Sauro, Herbert Scott-Brown, James Sexton, John T. Stan, Guy-Bart Tabor, Jeffrey J. Terry, Logan Vazquez Vilar, Marta Voigt, Christopher A. Wipat, Anil Zong, David Zundel, Zach Beal, Jacob Myers, Chris Massachusetts Institute of Technology. Department of Biological Engineering <jats:title>Abstract</jats:title> <jats:p>People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and other molecular species. Some typical practices and conventions have begun to emerge for such diagrams. The Synthetic Biology Open Language Visual (SBOL Visual) has been developed as a standard for organizing and systematizing such conventions in order to produce a coherent language for expressing the structure and function of genetic designs. This document details version 2.3 of SBOL Visual, which builds on the prior SBOL Visual 2.2 in several ways. First, the specification now includes higher-level “interactions with interactions,” such as an inducer molecule stimulating a repression interaction. Second, binding with a nucleic acid backbone can be shown by overlapping glyphs, as with other molecular complexes. Finally, a new “unspecified interaction” glyph is added for visualizing interactions whose nature is unknown, the “insulator” glyph is deprecated in favor of a new “inert DNA spacer” glyph, and the polypeptide region glyph is recommended for showing 2A sequences.</jats:p> 2021-11-10T21:15:25Z 2021-10-27T20:24:16Z 2021-11-10T21:15:25Z 2021-06 2021-09-10T17:18:21Z Article http://purl.org/eprint/type/JournalArticle 1613-4516 https://hdl.handle.net/1721.1/135615.2 en 10.1515/jib-2020-0045 Journal of Integrative Bioinformatics Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/octet-stream Walter de Gruyter GmbH De Gruyter
spellingShingle Baig, Hasan
Fontanarossa, Pedro
Kulkarni, Vishwesh
McLaughlin, James
Vaidyanathan, Prashant
Bartley, Bryan
Bhakta, Shyam
Bhatia, Swapnil
Bissell, Mike
Clancy, Kevin
Cox, Robert Sidney
Goñi Moreno, Angel
Gorochowski, Thomas
Grunberg, Raik
Lee, Jihwan
Luna, Augustin
Madsen, Curtis
Misirli, Goksel
Nguyen, Tramy
Le Novere, Nicolas
Palchick, Zachary
Pocock, Matthew
Roehner, Nicholas
Sauro, Herbert
Scott-Brown, James
Sexton, John T.
Stan, Guy-Bart
Tabor, Jeffrey J.
Terry, Logan
Vazquez Vilar, Marta
Voigt, Christopher A.
Wipat, Anil
Zong, David
Zundel, Zach
Beal, Jacob
Myers, Chris
Synthetic biology open language visual (SBOL Visual) version 2.3
title Synthetic biology open language visual (SBOL Visual) version 2.3
title_full Synthetic biology open language visual (SBOL Visual) version 2.3
title_fullStr Synthetic biology open language visual (SBOL Visual) version 2.3
title_full_unstemmed Synthetic biology open language visual (SBOL Visual) version 2.3
title_short Synthetic biology open language visual (SBOL Visual) version 2.3
title_sort synthetic biology open language visual sbol visual version 2 3
url https://hdl.handle.net/1721.1/135615.2
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