Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads

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<jats:p>Immunotherapies are a promising advance in cancer treatment. However, because only a subset of cancer patients benefits from these treatments it is important to find mechanisms that will broaden the responding patient population. Generally, tumors with high mutational burdens have the...

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Bibliographic Details
Main Authors: Lussier, Danielle M., Alspach, Elise, Ward, Jeffrey P., Miceli, Alexander P., Runci, Daniele, White, J. Michael, Mpoy, Cedric, Arthur, Cora D., Kohlmiller, Heather N., Jacks, Tyler, Artyomov, Maxim N., Rogers, Buck E., Schreiber, Robert D.
Other Authors: Howard Hughes Medical Institute
Format: Article
Language:English
Published: National Academy of Sciences 2022
Online Access:https://hdl.handle.net/1721.1/135643.2

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