Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

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Naive human embryonic stem cells (hESCs) have been isolated that more closely resemble the pre-implantation epiblast compared to conventional "primed" hESCs, but the signaling principles underlying these discrete stem cell states remain incompletely understood. Here, we describe the result...

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Bibliographic Details
Main Authors:	Khan, Shafqat A, Park, Kyoung-mi, Fischer, Laura A, Dong, Chen, Lungjangwa, Tenzin, Jimenez, Marta, Casalena, Dominick, Chew, Brian, Dietmann, Sabine, Auld, Douglas S, Jaenisch, Rudolf, Theunissen, Thorold W
Format:	Article
Language:	English
Published:	Elsevier BV 2021
Online Access:	https://hdl.handle.net/1721.1/135676

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