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1826210418429788160
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MIT
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© 2017 Nature America, Inc. The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with curing cancer. Unmet needs for organ and tissue preservation place enormous logistical limitations on transplantation, regenerative medicine, drug discovery, and a variety of rapidly advancing areas spanning biomedicine. A growing coalition of researchers, clinicians, advocacy organizations, academic institutions, and other stakeholders has assembled to address the unmet need for preservation advances, outlining remaining challenges and identifying areas of underinvestment and untapped opportunities. Meanwhile, recent discoveries provide proofs of principle for breakthroughs in a family of research areas surrounding biopreservation. These developments indicate that a new paradigm, integrating multiple existing preservation approaches and new technologies that have flourished in the past 10 years, could transform preservation research. Capitalizing on these opportunities will require engagement across many research areas and stakeholder groups. A coordinated effort is needed to expedite preservation advances that can transform several areas of medicine and medical science.
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| first_indexed |
2024-09-23T14:49:34Z
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Article
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| id |
mit-1721.1/135708
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| institution |
Massachusetts Institute of Technology
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| language |
English
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| last_indexed |
2024-09-23T14:49:34Z
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| publishDate |
2021
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| publisher |
Springer Nature
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dspace
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| spelling |
mit-1721.1/1357082022-09-29T10:49:21Z The promise of organ and tissue preservation to transform medicine © 2017 Nature America, Inc. The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with curing cancer. Unmet needs for organ and tissue preservation place enormous logistical limitations on transplantation, regenerative medicine, drug discovery, and a variety of rapidly advancing areas spanning biomedicine. A growing coalition of researchers, clinicians, advocacy organizations, academic institutions, and other stakeholders has assembled to address the unmet need for preservation advances, outlining remaining challenges and identifying areas of underinvestment and untapped opportunities. Meanwhile, recent discoveries provide proofs of principle for breakthroughs in a family of research areas surrounding biopreservation. These developments indicate that a new paradigm, integrating multiple existing preservation approaches and new technologies that have flourished in the past 10 years, could transform preservation research. Capitalizing on these opportunities will require engagement across many research areas and stakeholder groups. A coordinated effort is needed to expedite preservation advances that can transform several areas of medicine and medical science. 2021-10-27T20:28:55Z 2021-10-27T20:28:55Z 2017 2019-07-19T13:57:59Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/135708 en 10.1038/NBT.3889 Nature Biotechnology Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Springer Nature PMC
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| spellingShingle |
The promise of organ and tissue preservation to transform medicine
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| title |
The promise of organ and tissue preservation to transform medicine
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| title_full |
The promise of organ and tissue preservation to transform medicine
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| title_fullStr |
The promise of organ and tissue preservation to transform medicine
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| title_full_unstemmed |
The promise of organ and tissue preservation to transform medicine
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| title_short |
The promise of organ and tissue preservation to transform medicine
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| title_sort |
promise of organ and tissue preservation to transform medicine
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| url |
https://hdl.handle.net/1721.1/135708
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