Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers
© 2016 Elsevier Inc. Generic spinal motor neuron identity is established by cooperative binding of programming transcription factors (TFs), Isl1 and Lhx3, to motor-neuron-specific enhancers. How expression of effector genes is maintained following downregulation of programming TFs in maturing neuron...
Main Authors: | Rhee, Ho Sung, Closser, Michael, Guo, Yuchun, Bashkirova, Elizaveta V, Tan, G Christopher, Gifford, David K, Wichterle, Hynek |
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Format: | Article |
Language: | English |
Published: |
Elsevier BV
2021
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Online Access: | https://hdl.handle.net/1721.1/135733 |
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