Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions
<jats:p> T-cell identity is established by the expression of a clonotypic T-cell receptor (TCR), generated by somatic rearrangement of TCRα and β genes. The properties of the TCR determine both the degree of self-reactivity and the repertoire of antigens that can be recognized. For...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Royal Society
2021
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| Online Access: | https://hdl.handle.net/1721.1/135734 |
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