Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain

Porous silicon–graphene oxide core–shell nanoparticles for targeted delivery of siRNA to the injured brain

© 2016 The Royal Society of Chemistry. We report the synthesis, characterization, and assessment of a nanoparticle-based RNAi delivery platform that protects siRNA payloads against nuclease-induced degradation and efficiently delivers them to target cells. The nanocarrier is based on biodegradable m...

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Bibliographic Details
Main Authors: Joo, Jinmyoung, Kwon, Ester J, Kang, Jinyoung, Skalak, Matthew, Anglin, Emily J, Mann, Aman P, Ruoslahti, Erkki, Bhatia, Sangeeta N, Sailor, Michael J
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC) 2021
Online Access:https://hdl.handle.net/1721.1/135749

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