Optogenetics: Tools for Controlling Brain Cells with Light
<jats:p>The brain is made out of an incredible diversity of cells called neurons, which have different shapes, are made of different molecules, and that change in different ways in diseases. In optogenetics, microbial opsins, natural proteins that convert light into electrical signals, are gen...
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| Format: | Article |
| Language: | English |
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World Scientific Pub Co Pte Lt
2021
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| Online Access: | https://hdl.handle.net/1721.1/135916 |
| _version_ | 1826201038052392960 |
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| author | Boyden, Edward S |
| author_facet | Boyden, Edward S |
| author_sort | Boyden, Edward S |
| collection | MIT |
| description | <jats:p>The brain is made out of an incredible diversity of cells called neurons, which have different shapes, are made of different molecules, and that change in different ways in diseases. In optogenetics, microbial opsins, natural proteins that convert light into electrical signals, are genetically expressed in neurons. Then, light pulses can be used to turn neurons on, revealing how they trigger behaviors, disease states, or therapeutic effects, or to turn neurons off, revealing what functions or dysfunctions they are necessary for.</jats:p> |
| first_indexed | 2024-09-23T11:45:40Z |
| format | Article |
| id | mit-1721.1/135916 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:45:40Z |
| publishDate | 2021 |
| publisher | World Scientific Pub Co Pte Lt |
| record_format | dspace |
| spelling | mit-1721.1/1359162021-10-28T04:11:42Z Optogenetics: Tools for Controlling Brain Cells with Light Boyden, Edward S <jats:p>The brain is made out of an incredible diversity of cells called neurons, which have different shapes, are made of different molecules, and that change in different ways in diseases. In optogenetics, microbial opsins, natural proteins that convert light into electrical signals, are genetically expressed in neurons. Then, light pulses can be used to turn neurons on, revealing how they trigger behaviors, disease states, or therapeutic effects, or to turn neurons off, revealing what functions or dysfunctions they are necessary for.</jats:p> 2021-10-27T20:29:56Z 2021-10-27T20:29:56Z 2019 2021-03-11T18:57:44Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/135916 en 10.1142/S2529732519400133 Molecular Frontiers Journal Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf World Scientific Pub Co Pte Lt World Scientific |
| spellingShingle | Boyden, Edward S Optogenetics: Tools for Controlling Brain Cells with Light |
| title | Optogenetics: Tools for Controlling Brain Cells with Light |
| title_full | Optogenetics: Tools for Controlling Brain Cells with Light |
| title_fullStr | Optogenetics: Tools for Controlling Brain Cells with Light |
| title_full_unstemmed | Optogenetics: Tools for Controlling Brain Cells with Light |
| title_short | Optogenetics: Tools for Controlling Brain Cells with Light |
| title_sort | optogenetics tools for controlling brain cells with light |
| url | https://hdl.handle.net/1721.1/135916 |
| work_keys_str_mv | AT boydenedwards optogeneticstoolsforcontrollingbraincellswithlight |