Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex

Copyright © 2020 The Authors, Ribonucleotide reductases (RNRs) are a diverse family of enzymes that are alone capable of generating 2′-deoxynucleotides de novo and are thus critical in DNA biosynthesis and repair. The nucleotide reduction reaction in all RNRs requires the generation of a transient a...

Full description

Bibliographic Details
Main Authors: Kang, Gyunghoon, Taguchi, Alexander T, Stubbe, JoAnne, Drennan, Catherine L
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/136072