Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases

Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases

Slow progress in the fight against neurodegenerative diseases (NDs) motivates an urgent need for highly controlled in vitro systems to investigate organ-organ– and organ-immune–specific interactions relevant for disease pathophysiology. Of particular interest is the gut/microbiome-liver-brain axis f...

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Bibliographic Details
Main Authors: Trapecar, Martin, Wogram, Emile, Svoboda, Devon, Communal, Catherine, Omer, Attya, Lungjangwa, Tenzin, Sphabmixay, Pierre, Velazquez, Jason, Schneider, Kirsten, Wright, Charles W, Mildrum, Samuel, Hendricks, Austin, Levine, Stuart, Muffat, Julien, Lee, Meelim Jasmine, Lauffenburger, Douglas A, Trumper, David, Jaenisch, Rudolf, Griffith, Linda G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/136121

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