An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease

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© 2020 American Association for the Advancement of Science. All rights reserved. Anti-tumor necrosis factor (anti-TNF) therapy resistance is a major clinical challenge in inflammatory bowel disease (IBD), due, in part, to insufficient understanding of disease-site, protein-level mechanisms. Although...

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Main Authors: Brubaker, Douglas K, Kumar, Manu P, Chiswick, Evan L, Gregg, Cecil, Starchenko, Alina, Vega, Paige N, Southard-Smith, Austin N, Simmons, Alan J, Scoville, Elizabeth A, Coburn, Lori A, Wilson, Keith T, Lau, Ken S, Lauffenburger, Douglas A
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/136133

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