IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

© 2020, The Author(s), under exclusive licence to Springer Nature Limited. Interferon-induced transmembrane protein 3 (IFITM3) has previously been identified as an endosomal protein that blocks viral infection1–3. Here we studied clinical cohorts of patients with B cell leukaemia and lymphoma, and i...

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Main Authors: Lee, Jaewoong, Robinson, Mark E, Ma, Ning, Artadji, Dewan, Ahmed, Mohamed A, Xiao, Gang, Sadras, Teresa, Deb, Gauri, Winchester, Janet, Cosgun, Kadriye Nehir, Geng, Huimin, Chan, Lai N, Kume, Kohei, Miettinen, Teemu P, Zhang, Ye, Nix, Matthew A, Klemm, Lars, Chen, Chun Wei, Chen, Jianjun, Khairnar, Vishal, Wiita, Arun P, Thomas-Tikhonenko, Andrei, Farzan, Michael, Jung, Jae U, Weinstock, David M, Manalis, Scott R, Diamond, Michael S, Vaidehi, Nagarajan, Müschen, Markus
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/136158

Internet

https://hdl.handle.net/1721.1/136158

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