In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells

In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells

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© 2020, The Author(s). Microtubules (MTs) mediate mitosis, directional signaling, and are therapeutic targets in cancer. Yet in vivo analysis of cancer cell MT behavior within the tumor microenvironment remains challenging. Here we developed an imaging pipeline using plus-end tip tracking and intrav...

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Bibliographic Details
Main Authors: Luthria, Gaurav, Li, Ran, Wang, Stephanie, Prytyskach, Mark, Kohler, Rainer H, Lauffenburger, Douglas A, Mitchison, Timothy J, Weissleder, Ralph, Miller, Miles A
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/136161

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