n →π* Interactions Modulate the Disulfide Reduction Potential of Epidithiodiketopiperazines

Copyright © 2020 American Chemical Society. Epithiodiketopiperazines (ETPs) are a structurally complex class of fungal natural products with potent anticancer activity. In ETPs, the diketopiperazine ring is spanned by a disulfide bond that is constrained in a high-energy eclipsed conformation. We em...

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Bibliografski detalji
Glavni autori: Kilgore, Henry R, Olsson, Chase R, D’Angelo, Kyan A, Movassaghi, Mohammad, Raines, Ronald T
Format: Članak
Jezik:English
Izdano: American Chemical Society (ACS) 2021
Online pristup:https://hdl.handle.net/1721.1/136169