Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

© 2019 Elsevier Inc. The liver can substantially regenerate after injury, with both main epithelial cell types, hepatocytes and biliary epithelial cells (BECs), playing important roles in parenchymal regeneration. Beyond metabolic functions, BECs exhibit substantial plasticity and in some contexts c...

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Bibliographic Details
Main Authors: Pepe-Mooney, Brian J, Dill, Michael T, Alemany, Anna, Ordovas-Montanes, Jose, Matsushita, Yuki, Rao, Anuradha, Sen, Anushna, Miyazaki, Makoto, Anakk, Sayeepriyadarshini, Dawson, Paul A, Ono, Noriaki, Shalek, Alex K, van Oudenaarden, Alexander, Camargo, Fernando D
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/136180

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