Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic

Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic

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Copyright © 2019 American Chemical Society. Manipulation of the ubiquitin-proteasome pathway to achieve targeted silencing of cellular proteins has emerged as a reliable and customizable strategy for remodeling the mammalian proteome. One such approach involves engineering bifunctional proteins call...

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Bibliographic Details
Main Authors:	Ludwicki, Morgan B, Li, Jiahe, Stephens, Erin A, Roberts, Richard W, Koide, Shohei, Hammond, Paula T, DeLisa, Matthew P
Format:	Article
Language:	English
Published:	American Chemical Society (ACS) 2021
Online Access:	https://hdl.handle.net/1721.1/136198

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