Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic
Copyright © 2019 American Chemical Society. Manipulation of the ubiquitin-proteasome pathway to achieve targeted silencing of cellular proteins has emerged as a reliable and customizable strategy for remodeling the mammalian proteome. One such approach involves engineering bifunctional proteins call...
Main Authors: | Ludwicki, Morgan B, Li, Jiahe, Stephens, Erin A, Roberts, Richard W, Koide, Shohei, Hammond, Paula T, DeLisa, Matthew P |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2021
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Online Access: | https://hdl.handle.net/1721.1/136198 |
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