Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

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© 2020 Neuroblastoma (NB), derived from the neural crest (NC), is the most common pediatric extracranial solid tumor. Here, we establish a platform that allows the study of human NBs in mouse-human NC chimeras. Chimeric mice were produced by injecting human NC cells carrying NB relevant oncogenes in...

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Bibliographic Details
Main Authors: Cohen, Malkiel A, Zhang, Shupei, Sengupta, Satyaki, Ma, Haiting, Bell, George W, Horton, Brendan, Sharma, Bandana, George, Rani E, Spranger, Stefani, Jaenisch, Rudolf
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/136241
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