Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis
© 2019 Elsevier Inc. Bacteriophage libraries containing millions of variants of phage tail fiber motifs on a common structural scaffold give rise to infectious phages with expanded or altered host ranges, which may be useful for phage therapy efforts.
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV
2021
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| Online Access: | https://hdl.handle.net/1721.1/136451 |
| _version_ | 1811079736470798336 |
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| author | Yehl, Kevin Lemire, Sébastien Yang, Andrew C Ando, Hiroki Mimee, Mark Torres, Marcelo Der Torossian de la Fuente-Nunez, Cesar Lu, Timothy K |
| author2 | Massachusetts Institute of Technology. Synthetic Biology Center |
| author_facet | Massachusetts Institute of Technology. Synthetic Biology Center Yehl, Kevin Lemire, Sébastien Yang, Andrew C Ando, Hiroki Mimee, Mark Torres, Marcelo Der Torossian de la Fuente-Nunez, Cesar Lu, Timothy K |
| author_sort | Yehl, Kevin |
| collection | MIT |
| description | © 2019 Elsevier Inc. Bacteriophage libraries containing millions of variants of phage tail fiber motifs on a common structural scaffold give rise to infectious phages with expanded or altered host ranges, which may be useful for phage therapy efforts. |
| first_indexed | 2024-09-23T11:19:44Z |
| format | Article |
| id | mit-1721.1/136451 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:19:44Z |
| publishDate | 2021 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1364512024-03-20T20:25:08Z Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis Yehl, Kevin Lemire, Sébastien Yang, Andrew C Ando, Hiroki Mimee, Mark Torres, Marcelo Der Torossian de la Fuente-Nunez, Cesar Lu, Timothy K Massachusetts Institute of Technology. Synthetic Biology Center Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics Massachusetts Institute of Technology. Research Laboratory of Electronics Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Biological Engineering © 2019 Elsevier Inc. Bacteriophage libraries containing millions of variants of phage tail fiber motifs on a common structural scaffold give rise to infectious phages with expanded or altered host ranges, which may be useful for phage therapy efforts. 2021-10-27T20:35:26Z 2021-10-27T20:35:26Z 2019 2021-01-28T19:32:22Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/136451 en 10.1016/J.CELL.2019.09.015 Cell Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV PMC |
| spellingShingle | Yehl, Kevin Lemire, Sébastien Yang, Andrew C Ando, Hiroki Mimee, Mark Torres, Marcelo Der Torossian de la Fuente-Nunez, Cesar Lu, Timothy K Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis |
| title | Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis |
| title_full | Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis |
| title_fullStr | Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis |
| title_full_unstemmed | Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis |
| title_short | Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis |
| title_sort | engineering phage host range and suppressing bacterial resistance through phage tail fiber mutagenesis |
| url | https://hdl.handle.net/1721.1/136451 |
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