DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8 + T Cell Compartment by Negatively Regulating Tonic TCR Triggering

DOCK2 Sets the Threshold for Entry into the Virtual Memory CD8 + T Cell Compartment by Negatively Regulating Tonic TCR Triggering

Copyright © 2019 by The American Association of Immunologists, Inc. The control of cytoskeletal dynamics by dedicator of cytokinesis 2 (DOCK2), a hematopoietic cell-specific actin effector protein, has been implicated in TCR signaling and T cell migration. Biallelic mutations in Dock2 have been iden...

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Bibliographic Details
Main Authors: Mahajan, Vinay S, Demissie, Ezana, Alsufyani, Faisal, Kumari, Sudha, Yuen, Grace J, Viswanadham, Vinayak, Huang, Andrew, Tran, Johnson Q, Moon, James J, Irvine, Darrell J, Pillai, Shiv
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: The American Association of Immunologists 2021
Online Access:https://hdl.handle.net/1721.1/136611

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