A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T
© 2019 Functional magnetic resonance imaging (fMRI) in monkeys is important for bridging the gap between invasive animal brain studies and non-invasive human brain studies. To resolve the finer functional structure of the monkey brain, ultra-high-field (UHF) MR is essential, and high-performance, cl...
| Κύριοι συγγραφείς: | , , , , , , , , , , |
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| Άλλοι συγγραφείς: | |
| Μορφή: | Άρθρο |
| Γλώσσα: | English |
| Έκδοση: |
Elsevier BV
2021
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| Διαθέσιμο Online: | https://hdl.handle.net/1721.1/136614 |
| _version_ | 1826196370288017408 |
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| author | Gao, Yang Mareyam, Azma Sun, Yi Witzel, Thomas Arango, Nicolas Kuang, Irene White, Jacob Roe, Anna Wang Wald, Lawrence Stockmann, Jason Zhang, Xiaotong |
| author2 | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
| author_facet | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Gao, Yang Mareyam, Azma Sun, Yi Witzel, Thomas Arango, Nicolas Kuang, Irene White, Jacob Roe, Anna Wang Wald, Lawrence Stockmann, Jason Zhang, Xiaotong |
| author_sort | Gao, Yang |
| collection | MIT |
| description | © 2019 Functional magnetic resonance imaging (fMRI) in monkeys is important for bridging the gap between invasive animal brain studies and non-invasive human brain studies. To resolve the finer functional structure of the monkey brain, ultra-high-field (UHF) MR is essential, and high-performance, close-fitting RF receive coils are typically desired to fully leverage the intrinsic gains provided by UHF MRI. Moreover, static field (B0) inhomogeneity arising from the tissue susceptibility interface is more severe at UHF, presenting an obstacle to achieving high-resolution fMRI. B0 shim of the monkey head is challenging due to its smaller size and more complex sources of B0 offsets in multi-modal imaging tasks. In the present work, we have customized an array coil for lightly-anesthetized monkey fMRI in the 7T human scanner that combines RF and multi-coil (MC) B0 shim functionality (also referred to as AC/DC coils) to provide high imaging SNR and high-spatial-order, rapidly switchable B0-shim capability. Additional space was retained on the coil to render it compatible with monkey multi-modal imaging studies. Both MC global (whole-volume) and dynamic (slice-optimized) shim methods were tested and evaluated, and the benefits of MC shim for fMRI experiments was also studied. A minor reduction in RF coil performance was found after introducing additional B0 shim circuitry. However, the proposed RF coil provided higher image SNR and more uniform contrast compared to a commercially available coil for human knee imaging. Compared with static 2nd-order shim, the B0 inhomogeneity was reduced by 56.8%, and 95-percentile B0 offset was reduced to within 28.2 Hz through MC shim, versus 68.7 Hz with 2nd-order static shim. As a result, functional image quality could be improved, and brain activation can be better detected using the proposed AC/DC monkey coil. |
| first_indexed | 2024-09-23T10:25:49Z |
| format | Article |
| id | mit-1721.1/136614 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T10:25:49Z |
| publishDate | 2021 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1366142023-09-28T19:48:02Z A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T Gao, Yang Mareyam, Azma Sun, Yi Witzel, Thomas Arango, Nicolas Kuang, Irene White, Jacob Roe, Anna Wang Wald, Lawrence Stockmann, Jason Zhang, Xiaotong Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science © 2019 Functional magnetic resonance imaging (fMRI) in monkeys is important for bridging the gap between invasive animal brain studies and non-invasive human brain studies. To resolve the finer functional structure of the monkey brain, ultra-high-field (UHF) MR is essential, and high-performance, close-fitting RF receive coils are typically desired to fully leverage the intrinsic gains provided by UHF MRI. Moreover, static field (B0) inhomogeneity arising from the tissue susceptibility interface is more severe at UHF, presenting an obstacle to achieving high-resolution fMRI. B0 shim of the monkey head is challenging due to its smaller size and more complex sources of B0 offsets in multi-modal imaging tasks. In the present work, we have customized an array coil for lightly-anesthetized monkey fMRI in the 7T human scanner that combines RF and multi-coil (MC) B0 shim functionality (also referred to as AC/DC coils) to provide high imaging SNR and high-spatial-order, rapidly switchable B0-shim capability. Additional space was retained on the coil to render it compatible with monkey multi-modal imaging studies. Both MC global (whole-volume) and dynamic (slice-optimized) shim methods were tested and evaluated, and the benefits of MC shim for fMRI experiments was also studied. A minor reduction in RF coil performance was found after introducing additional B0 shim circuitry. However, the proposed RF coil provided higher image SNR and more uniform contrast compared to a commercially available coil for human knee imaging. Compared with static 2nd-order shim, the B0 inhomogeneity was reduced by 56.8%, and 95-percentile B0 offset was reduced to within 28.2 Hz through MC shim, versus 68.7 Hz with 2nd-order static shim. As a result, functional image quality could be improved, and brain activation can be better detected using the proposed AC/DC monkey coil. 2021-10-27T20:36:14Z 2021-10-27T20:36:14Z 2020 2021-01-25T16:27:02Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/136614 en 10.1016/J.NEUROIMAGE.2019.116396 NeuroImage Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV Elsevier |
| spellingShingle | Gao, Yang Mareyam, Azma Sun, Yi Witzel, Thomas Arango, Nicolas Kuang, Irene White, Jacob Roe, Anna Wang Wald, Lawrence Stockmann, Jason Zhang, Xiaotong A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
| title | A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
| title_full | A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
| title_fullStr | A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
| title_full_unstemmed | A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
| title_short | A 16-channel AC/DC array coil for anesthetized monkey whole-brain imaging at 7T |
| title_sort | 16 channel ac dc array coil for anesthetized monkey whole brain imaging at 7t |
| url | https://hdl.handle.net/1721.1/136614 |
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