The role of prefrontal cortex in the control of feature attention in area V4
© 2019, The Author(s). When searching for an object in a cluttered scene, we can use our memory of the target object features to guide our search, and the responses of neurons in multiple cortical visual areas are enhanced when their receptive field contains a stimulus sharing target object features...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC
2021
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| Online Access: | https://hdl.handle.net/1721.1/136635 |
| _version_ | 1811080780507512832 |
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| author | Bichot, Narcisse P Xu, Rui Ghadooshahy, Azriel Williams, Michael L Desimone, Robert |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Bichot, Narcisse P Xu, Rui Ghadooshahy, Azriel Williams, Michael L Desimone, Robert |
| author_sort | Bichot, Narcisse P |
| collection | MIT |
| description | © 2019, The Author(s). When searching for an object in a cluttered scene, we can use our memory of the target object features to guide our search, and the responses of neurons in multiple cortical visual areas are enhanced when their receptive field contains a stimulus sharing target object features. Here we tested the role of the ventral prearcuate region (VPA) of prefrontal cortex in the control of feature attention in cortical visual area V4. VPA was unilaterally inactivated in monkeys performing a free-viewing visual search for a target stimulus in an array of stimuli, impairing monkeys’ ability to find the target in the array in the affected hemifield, but leaving intact their ability to make saccades to targets presented alone. Simultaneous recordings in V4 revealed that the effects of feature attention on V4 responses were eliminated or greatly reduced while leaving the effects of spatial attention on responses intact. Altogether, the results suggest that feedback from VPA modulates processing in visual cortex during attention to object features. |
| first_indexed | 2024-09-23T11:36:44Z |
| format | Article |
| id | mit-1721.1/136635 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:36:44Z |
| publishDate | 2021 |
| publisher | Springer Science and Business Media LLC |
| record_format | dspace |
| spelling | mit-1721.1/1366352023-09-27T20:41:10Z The role of prefrontal cortex in the control of feature attention in area V4 Bichot, Narcisse P Xu, Rui Ghadooshahy, Azriel Williams, Michael L Desimone, Robert Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT © 2019, The Author(s). When searching for an object in a cluttered scene, we can use our memory of the target object features to guide our search, and the responses of neurons in multiple cortical visual areas are enhanced when their receptive field contains a stimulus sharing target object features. Here we tested the role of the ventral prearcuate region (VPA) of prefrontal cortex in the control of feature attention in cortical visual area V4. VPA was unilaterally inactivated in monkeys performing a free-viewing visual search for a target stimulus in an array of stimuli, impairing monkeys’ ability to find the target in the array in the affected hemifield, but leaving intact their ability to make saccades to targets presented alone. Simultaneous recordings in V4 revealed that the effects of feature attention on V4 responses were eliminated or greatly reduced while leaving the effects of spatial attention on responses intact. Altogether, the results suggest that feedback from VPA modulates processing in visual cortex during attention to object features. 2021-10-27T20:36:22Z 2021-10-27T20:36:22Z 2019 2021-03-25T13:27:58Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/136635 en 10.1038/S41467-019-13761-7 Nature Communications Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Springer Science and Business Media LLC Nature |
| spellingShingle | Bichot, Narcisse P Xu, Rui Ghadooshahy, Azriel Williams, Michael L Desimone, Robert The role of prefrontal cortex in the control of feature attention in area V4 |
| title | The role of prefrontal cortex in the control of feature attention in area V4 |
| title_full | The role of prefrontal cortex in the control of feature attention in area V4 |
| title_fullStr | The role of prefrontal cortex in the control of feature attention in area V4 |
| title_full_unstemmed | The role of prefrontal cortex in the control of feature attention in area V4 |
| title_short | The role of prefrontal cortex in the control of feature attention in area V4 |
| title_sort | role of prefrontal cortex in the control of feature attention in area v4 |
| url | https://hdl.handle.net/1721.1/136635 |
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