Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections
Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding liquid is expelled from the constraining microfluidic channel thr...
| Main Authors: | , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing
2021
|
| Online Access: | https://hdl.handle.net/1721.1/136655 |
| _version_ | 1811097407422726144 |
|---|---|
| author | Oyarte Gálvez, Loreto Fraters, Arjan Offerhaus, Herman L Versluis, Michel Hunter, Ian W Fernández Rivas, David |
| author2 | Massachusetts Institute of Technology. Department of Mechanical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Mechanical Engineering Oyarte Gálvez, Loreto Fraters, Arjan Offerhaus, Herman L Versluis, Michel Hunter, Ian W Fernández Rivas, David |
| author_sort | Oyarte Gálvez, Loreto |
| collection | MIT |
| description | Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding liquid is expelled from the constraining microfluidic channel through a nozzle, creating a jet. The characteristics of the resulting liquid jet were imaged using ultra-fast imaging techniques. Here, we provide a phenomenological description of the jet shapes and velocities and compare them with a boundary integral numerical model. We define the parameter regime, varying jet speed, taper geometry, and liquid volume for optimal printing, injection, and spray applications. These results are important for the design of energy-efficient needle-free jet injectors based on microfluidic thermocavitation. |
| first_indexed | 2024-09-23T16:59:02Z |
| format | Article |
| id | mit-1721.1/136655 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T16:59:02Z |
| publishDate | 2021 |
| publisher | AIP Publishing |
| record_format | dspace |
| spelling | mit-1721.1/1366552023-01-11T18:48:12Z Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections Oyarte Gálvez, Loreto Fraters, Arjan Offerhaus, Herman L Versluis, Michel Hunter, Ian W Fernández Rivas, David Massachusetts Institute of Technology. Department of Mechanical Engineering Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding liquid is expelled from the constraining microfluidic channel through a nozzle, creating a jet. The characteristics of the resulting liquid jet were imaged using ultra-fast imaging techniques. Here, we provide a phenomenological description of the jet shapes and velocities and compare them with a boundary integral numerical model. We define the parameter regime, varying jet speed, taper geometry, and liquid volume for optimal printing, injection, and spray applications. These results are important for the design of energy-efficient needle-free jet injectors based on microfluidic thermocavitation. 2021-10-27T20:36:27Z 2021-10-27T20:36:27Z 2020 2020-07-21T17:05:10Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/136655 en 10.1063/1.5140264 Journal of Applied Physics Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf AIP Publishing arXiv |
| spellingShingle | Oyarte Gálvez, Loreto Fraters, Arjan Offerhaus, Herman L Versluis, Michel Hunter, Ian W Fernández Rivas, David Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections |
| title | Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections |
| title_full | Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections |
| title_fullStr | Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections |
| title_full_unstemmed | Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections |
| title_short | Microfluidics control the ballistic energy of thermocavitation liquid jets for needle-free injections |
| title_sort | microfluidics control the ballistic energy of thermocavitation liquid jets for needle free injections |
| url | https://hdl.handle.net/1721.1/136655 |
| work_keys_str_mv | AT oyartegalvezloreto microfluidicscontroltheballisticenergyofthermocavitationliquidjetsforneedlefreeinjections AT fratersarjan microfluidicscontroltheballisticenergyofthermocavitationliquidjetsforneedlefreeinjections AT offerhaushermanl microfluidicscontroltheballisticenergyofthermocavitationliquidjetsforneedlefreeinjections AT versluismichel microfluidicscontroltheballisticenergyofthermocavitationliquidjetsforneedlefreeinjections AT hunterianw microfluidicscontroltheballisticenergyofthermocavitationliquidjetsforneedlefreeinjections AT fernandezrivasdavid microfluidicscontroltheballisticenergyofthermocavitationliquidjetsforneedlefreeinjections |