Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus

Abstract Background Vaccines comprising recombinant subunit proteins are well-suited to low-cost and high-volume production for global use. The design of manufacturing processes to produce subunit vaccines depends, however, on the inherent biophysica...

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Bibliographic Details
Main Authors: Dalvie, Neil C, Brady, Joseph R, Crowell, Laura E, Tracey, Mary K, Biedermann, Andrew M, Kaur, Kawaljit, Hickey, John M, Kristensen, D. L, Bonnyman, Alexandra D, Rodriguez-Aponte, Sergio A, Whittaker, Charles A, Bok, Marina, Vega, Celina, Mukhopadhyay, Tarit K, Joshi, Sangeeta B, Volkin, David B
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/136780

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