The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients

Abstract The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answ...

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Main Authors: Abbott, Keene L, Vander Heiden, Matthew G
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/136805
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author Abbott, Keene L
Vander Heiden, Matthew G
author_facet Abbott, Keene L
Vander Heiden, Matthew G
author_sort Abbott, Keene L
collection MIT
description Abstract The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host.
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spelling mit-1721.1/1368052021-11-02T03:03:05Z The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients Abbott, Keene L Vander Heiden, Matthew G Abstract The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host. 2021-11-01T14:33:30Z 2021-11-01T14:33:30Z 2021-05-10 2021-05-16T03:11:46Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/136805 BMC Biology. 2021 May 10;19(1):92 PUBLISHER_CC en https://doi.org/10.1186/s12915-021-01027-y Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ The Author(s) application/pdf BioMed Central BioMed Central
spellingShingle Abbott, Keene L
Vander Heiden, Matthew G
The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_full The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_fullStr The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_full_unstemmed The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_short The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients
title_sort cat sir is out of the bag tumors prefer host rather than dietary nutrients
url https://hdl.handle.net/1721.1/136805
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