Function of Drosophila Synaptotagmins in membrane trafficking at synapses

Function of Drosophila Synaptotagmins in membrane trafficking at synapses

Show other versions (1)

Abstract The Synaptotagmin (SYT) family of proteins play key roles in regulating membrane trafficking at neuronal synapses. Using both Ca2+-dependent and Ca2+-independent interactions, several SYT isoforms participate in synchronous and asynchronous fusion of synaptic vesicles (SVs) w...

Full description

Bibliographic Details
Main Authors:	Quiñones-Frías, Mónica C., Littleton, J. T.
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	English
Published:	Springer International Publishing 2021
Online Access:	https://hdl.handle.net/1721.1/136813

Similar Items

Function of Drosophila Synaptotagmins in membrane trafficking at synapses
by: Quiñones-Frías, Mónica C., et al.
Published: (2021)

Characterization of synaptotagmin 7 function in neurotransmission and its subcellular localization at synapses
by: Quiñones-Frías, Mónica C.(Mónica Cristina)
Published: (2020)

Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner
by: Guan, Zhuo, et al.
Published: (2021)

Drosophila Synaptotagmin 7 negatively regulates synaptic vesicle release and replenishment in a dosage-dependent manner
by: Zhuo Guan, et al.
Published: (2020-04-01)

Molecular genetic characterization of the Drosophila synaptotagmin family
by: Adolfsen William W. (William Wallis)
Published: (2006)

Triple Function of Synaptotagmin 7 Ensures Efficiency of High-Frequency Transmission at Central GABAergic Synapses
by: Chong Chen, et al.
Published: (2017-11-01)

SGIP1α functions as a selective endocytic adaptor for the internalization of synaptotagmin 1 at synapses
by: Sang-Eun Lee, et al.
Published: (2019-05-01)

Cytotoxic Granule Trafficking and Fusion in Synaptotagmin7-Deficient Cytotoxic T Lymphocytes
by: Marwa Sleiman, et al.
Published: (2020-05-01)

Synaptotagmin 2 Is the Fast Ca2+ Sensor at a Central Inhibitory Synapse
by: Chong Chen, et al.
Published: (2017-01-01)

Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4
by: Vinita Bharat, et al.
Published: (2017-11-01)

Transmembrane tethering of synaptotagmin to synaptic vesicles controls multiple modes of neurotransmitter release
by: Littleton, J. Troy, et al.
Published: (2015)

Synaptotagmin Ca2+ Sensors and Their Spatial Coupling to Presynaptic Cav Channels in Central Cortical Synapses
by: Grit Bornschein, et al.
Published: (2019-01-01)

Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration
by: Kevin C. Courtney, et al.
Published: (2023-11-01)

Insights into membrane association of the SMP domain of extended synaptotagmin
by: Yunyun Wang, et al.
Published: (2023-03-01)

Control of plasma membrane lipid homeostasis by the extended synaptotagmins
by: Saheki, Yasunori, et al.
Published: (2016)

Characterization of developmental and molecular factors underlying release heterogeneity at Drosophila synapses
by: Yulia Akbergenova, et al.
Published: (2018-07-01)

Characterization of developmental and molecular factors underlying release heterogeneity at Drosophila synapses
by: Cunningham, Karen L, et al.
Published: (2018)

The Extended-Synaptotagmins
by: Saheki, Yasunori, et al.
Published: (2017)

Differential regulation of synchronous versus asynchronous neurotransmitter release by the C2 domains of synaptotagmin 1
by: Yoshihara, Motojiro, et al.
Published: (2014)

Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains
by: Littleton, J. Troy, et al.
Published: (2010)

Genetic Analysis of Synaptotagmin C2 Domain Specificity in Regulating Spontaneous and Evoked Neurotransmitter Release
by: Lee, Jihye, et al.
Published: (2013)

ER to synapse trafficking of NMDA receptors
by: Martin eHorak, et al.
Published: (2014-11-01)

The role of extended synaptotagmin at membrane contact sites in cancer research
by: Yuetian Pan, et al.
Published: (2023-11-01)

Electrostatic regulation of the cis- and trans-membrane interactions of synaptotagmin-1
by: Houda Yasmine Ali Moussa, et al.
Published: (2022-12-01)

Endoplasmic reticulum - plasma membrane crosstalk mediated by the extended synaptotagmins
by: Saheki, Yasunori
Published: (2017)

The Functional Significance of Synaptotagmin Diversity in Neuroendocrine Secretion
by: Paanteha K Moghadam, et al.
Published: (2013-09-01)

Complexin Controls Spontaneous and Evoked Neurotransmitter Release by Regulating the Timing and Properties of Synaptotagmin Activity
by: Akbergenova, Yulia, et al.
Published: (2013)

Synaptotagmin 7 switches short-term synaptic plasticity from depression to facilitation by suppressing synaptic transmission
by: Fujii, Takaaki, et al.
Published: (2021)

Synaptotagmin 7 switches short-term synaptic plasticity from depression to facilitation by suppressing synaptic transmission
by: Takaaki Fujii, et al.
Published: (2021-02-01)

Orchestration of Immunological Synapse Assembly by Vesicular Trafficking
by: Anna Onnis, et al.
Published: (2019-07-01)

Biological roles of plant synaptotagmins
by: Francisco Benitez-Fuente, et al.
Published: (2023-09-01)

The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling
by: Kathryn P Harris, et al.
Published: (2016-05-01)

Synapse development in health and disease
by: Melom, Jan Elizabeth, et al.
Published: (2016)

Transmission, Development, and Plasticity of Synapses
by: Littleton, J. Troy, et al.
Published: (2017)

Drosophila studies support a role for a presynaptic synaptotagmin mutation in a human congenital myasthenic syndrome.
by: Mallory C Shields, et al.
Published: (2017-01-01)

The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling
by: Zhang, Yao, et al.
Published: (2016)

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca²⁺ cooperativity of vesicle fusion
by: Guan, Zhuo, et al.
Published: (2018)

Upregulation of synaptotagmin IV inhibits transmitter release in PC12 cells with targeted synaptotagmin I knockdown
by: Moore-Dotson Johnnie M, et al.
Published: (2010-08-01)

Synaptotagmin-1 C2B domain interacts simultaneously with SNAREs and membranes to promote membrane fusion
by: Shen Wang, et al.
Published: (2016-04-01)

A synaptotagmin suppressor screen indicates SNARE binding controls the timing and Ca2+ cooperativity of vesicle fusion
by: Zhuo Guan, et al.
Published: (2017-09-01)