A Model for Resource Competition in CRISPR-Mediated Gene Repression

© 2018 IEEE. CRISPR-mediated gene regulation is known for its ability to control multiple targets simultaneously due to its modular nature: the same dCas9 effector can target different genes simply by changing the associated gRNA. However, multiplexing requires the sharing of limited amounts of dCas...

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Bibliographic Details
Main Authors: Chen, Pin-Yi, Qian, Yili, Del Vecchio, Domitilla
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: IEEE 2021
Online Access:https://hdl.handle.net/1721.1/138033

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