A Model for Resource Competition in CRISPR-Mediated Gene Repression
© 2018 IEEE. CRISPR-mediated gene regulation is known for its ability to control multiple targets simultaneously due to its modular nature: the same dCas9 effector can target different genes simply by changing the associated gRNA. However, multiplexing requires the sharing of limited amounts of dCas...
Main Authors: | Chen, Pin-Yi, Qian, Yili, Del Vecchio, Domitilla |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | English |
Published: |
IEEE
2021
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Online Access: | https://hdl.handle.net/1721.1/138033 |
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