ASIC design and data communications for the Boston retinal prosthesis

We report on the design and testing of a custom application-specific integrated circuit (ASIC) that has been developed as a key component of the Boston retinal prosthesis. This device has been designed for patients who are blind due to age-related macular degeneration or retinitis pigmentosa. Key sa...

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Main Authors: Shire, D. B., Ellersick, W., Kelly, S. K., Doyle, P., Priplata, A., Drohan, W., Mendoza, O., Gingerich, M., McKee, B., Wyatt, J. L., Rizzo, J. F.
Format: Article
Language:English
Published: IEEE 2021
Online Access:https://hdl.handle.net/1721.1/138044
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author Shire, D. B.
Ellersick, W.
Kelly, S. K.
Doyle, P.
Priplata, A.
Drohan, W.
Mendoza, O.
Gingerich, M.
McKee, B.
Wyatt, J. L.
Rizzo, J. F.
author_facet Shire, D. B.
Ellersick, W.
Kelly, S. K.
Doyle, P.
Priplata, A.
Drohan, W.
Mendoza, O.
Gingerich, M.
McKee, B.
Wyatt, J. L.
Rizzo, J. F.
author_sort Shire, D. B.
collection MIT
description We report on the design and testing of a custom application-specific integrated circuit (ASIC) that has been developed as a key component of the Boston retinal prosthesis. This device has been designed for patients who are blind due to age-related macular degeneration or retinitis pigmentosa. Key safety and communication features of the low-power ASIC are described, as are the highly configurable neural stimulation current waveforms that are delivered to its greater than 256 output electrodes. The ASIC was created using an 0.18 micron Si fabrication process utilizing standard 1.8 volt CMOS transistors as well as 20 volt lightly doped drain FETs. The communication system receives frequency-shift keyed inputs at 6.78 MHz from an implanted secondary coil, and transmits data back to the control unit through a lower-bandwidth channel that employs load-shift keying. The design's safety is ensured by on-board electrode voltage monitoring, stimulus charge limits, error checking of data transmitted to the implant, and comprehensive self-test and performance monitoring features. Each stimulus cycle is initiated by a transmitted word with a full 32-bit error check code. Taken together, these features allow researchers to safely and wirelessly tailor retinal stimulation and vision recovery for each patient.
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spelling mit-1721.1/1380442021-11-10T03:22:34Z ASIC design and data communications for the Boston retinal prosthesis Shire, D. B. Ellersick, W. Kelly, S. K. Doyle, P. Priplata, A. Drohan, W. Mendoza, O. Gingerich, M. McKee, B. Wyatt, J. L. Rizzo, J. F. We report on the design and testing of a custom application-specific integrated circuit (ASIC) that has been developed as a key component of the Boston retinal prosthesis. This device has been designed for patients who are blind due to age-related macular degeneration or retinitis pigmentosa. Key safety and communication features of the low-power ASIC are described, as are the highly configurable neural stimulation current waveforms that are delivered to its greater than 256 output electrodes. The ASIC was created using an 0.18 micron Si fabrication process utilizing standard 1.8 volt CMOS transistors as well as 20 volt lightly doped drain FETs. The communication system receives frequency-shift keyed inputs at 6.78 MHz from an implanted secondary coil, and transmits data back to the control unit through a lower-bandwidth channel that employs load-shift keying. The design's safety is ensured by on-board electrode voltage monitoring, stimulus charge limits, error checking of data transmitted to the implant, and comprehensive self-test and performance monitoring features. Each stimulus cycle is initiated by a transmitted word with a full 32-bit error check code. Taken together, these features allow researchers to safely and wirelessly tailor retinal stimulation and vision recovery for each patient. 2021-11-09T19:08:19Z 2021-11-09T19:08:19Z 2012-08 2019-08-16T17:22:50Z Article http://purl.org/eprint/type/ConferencePaper https://hdl.handle.net/1721.1/138044 Shire, D. B., Ellersick, W., Kelly, S. K., Doyle, P., Priplata, A. et al. 2012. "ASIC design and data communications for the Boston retinal prosthesis." en 10.1109/embc.2012.6345927 Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf IEEE PMC
spellingShingle Shire, D. B.
Ellersick, W.
Kelly, S. K.
Doyle, P.
Priplata, A.
Drohan, W.
Mendoza, O.
Gingerich, M.
McKee, B.
Wyatt, J. L.
Rizzo, J. F.
ASIC design and data communications for the Boston retinal prosthesis
title ASIC design and data communications for the Boston retinal prosthesis
title_full ASIC design and data communications for the Boston retinal prosthesis
title_fullStr ASIC design and data communications for the Boston retinal prosthesis
title_full_unstemmed ASIC design and data communications for the Boston retinal prosthesis
title_short ASIC design and data communications for the Boston retinal prosthesis
title_sort asic design and data communications for the boston retinal prosthesis
url https://hdl.handle.net/1721.1/138044
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