Boosting Natural Killer Cell Therapies in Glioblastoma Multiforme Using Supramolecular Cationic Inhibitors of Heat Shock Protein 90

Boosting Natural Killer Cell Therapies in Glioblastoma Multiforme Using Supramolecular Cationic Inhibitors of Heat Shock Protein 90

<jats:p>Allogeneic natural killer (aNK) cell adoptive therapy has the potential to dramatically impact clinical outcomes of glioblastoma multiforme (GBM). However, in order to exert therapeutic activity, NK cells require tumor expression of ligands for activating receptors, such as MHC Class I...

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Bibliographic Details
Main Authors: Saha, Tanmoy, van Vliet, Amanda A., Cui, Chunxiao, Macias, Jorge Jimenez, Kulkarni, Arpita, Pham, Luu Nhat, Lawler, Sean, Spanholtz, Jan, Georgoudaki, Anna-Maria, Duru, Adil Doganay, Goldman, Aaron
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Frontiers Media SA 2021
Online Access:https://hdl.handle.net/1721.1/138500

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