Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography

© 2020 IOP Publishing Ltd. Aseptic loosening, or loss of implant fixation, is a common complication following total joint replacement. Revision surgeries cost the healthcare system over $8 billion annually in the United States. Despite the prevalence of aseptic loosening, timely and accurate detecti...

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Main Authors: Ghaednia, H, Owens, CE, Roberts, R, Tallman, TN, Hart, A John, Varadarajan, KM
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: IOP Publishing 2021
Online Access:https://hdl.handle.net/1721.1/138765.2
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author Ghaednia, H
Owens, CE
Roberts, R
Tallman, TN
Hart, A John
Varadarajan, KM
author2 Massachusetts Institute of Technology. Department of Mechanical Engineering
author_facet Massachusetts Institute of Technology. Department of Mechanical Engineering
Ghaednia, H
Owens, CE
Roberts, R
Tallman, TN
Hart, A John
Varadarajan, KM
author_sort Ghaednia, H
collection MIT
description © 2020 IOP Publishing Ltd. Aseptic loosening, or loss of implant fixation, is a common complication following total joint replacement. Revision surgeries cost the healthcare system over $8 billion annually in the United States. Despite the prevalence of aseptic loosening, timely and accurate detection remains a challenge because traditional imaging modalities, such as plain radiographs, struggle to reliably detect the early stages of implant loosening. Motivated by this challenge, we present a novel approach for in vivo monitoring and failure detection of cemented joint replacements. Poly(methyl methacrylate) (PMMA) bone cement is modified with low volume fractions of chopped carbon fiber (CF) to impart piezoresistive-based self-sensing. Electrical impedance tomography (EIT) is then used to detect and monitor load-induced deformation and fracture of CF/PMMA in a phantom tank. We therefore show that EIT indeed is able to detect loading force on a prosthetic surrogate, distinguish between increasing load magnitudes, detect failure of implant fixation, and even distinguish between cement cracking and cement de-bonding without direct contact to the surrogate. Because EIT is a low-cost, physiologically benign, and potentially real-time imaging modality, the feasibility study herein presented could positively impact orthopedic researchers by providing, via in vivo monitoring, insight into the factors that initiate aseptic loosening.
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spelling mit-1721.1/138765.22021-12-22T18:38:16Z Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography Ghaednia, H Owens, CE Roberts, R Tallman, TN Hart, A John Varadarajan, KM Massachusetts Institute of Technology. Department of Mechanical Engineering © 2020 IOP Publishing Ltd. Aseptic loosening, or loss of implant fixation, is a common complication following total joint replacement. Revision surgeries cost the healthcare system over $8 billion annually in the United States. Despite the prevalence of aseptic loosening, timely and accurate detection remains a challenge because traditional imaging modalities, such as plain radiographs, struggle to reliably detect the early stages of implant loosening. Motivated by this challenge, we present a novel approach for in vivo monitoring and failure detection of cemented joint replacements. Poly(methyl methacrylate) (PMMA) bone cement is modified with low volume fractions of chopped carbon fiber (CF) to impart piezoresistive-based self-sensing. Electrical impedance tomography (EIT) is then used to detect and monitor load-induced deformation and fracture of CF/PMMA in a phantom tank. We therefore show that EIT indeed is able to detect loading force on a prosthetic surrogate, distinguish between increasing load magnitudes, detect failure of implant fixation, and even distinguish between cement cracking and cement de-bonding without direct contact to the surrogate. Because EIT is a low-cost, physiologically benign, and potentially real-time imaging modality, the feasibility study herein presented could positively impact orthopedic researchers by providing, via in vivo monitoring, insight into the factors that initiate aseptic loosening. 2021-12-22T18:38:14Z 2021-12-22T15:54:11Z 2021-12-22T18:38:14Z 2020 2021-12-22T15:43:50Z Article http://purl.org/eprint/type/JournalArticle 1361-665X https://hdl.handle.net/1721.1/138765.2 Ghaednia, H, Owens, CE, Roberts, R, Tallman, TN, Hart, AJ et al. 2020. "Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography." Smart Materials and Structures, 29 (8). en https://dx.doi.org/10.1088/1361-665X/AB874F Smart Materials and Structures Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/octet-stream IOP Publishing arXiv
spellingShingle Ghaednia, H
Owens, CE
Roberts, R
Tallman, TN
Hart, A John
Varadarajan, KM
Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
title Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
title_full Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
title_fullStr Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
title_full_unstemmed Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
title_short Interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
title_sort interfacial load monitoring and failure detection in total joint replacements via piezoresistive bone cement and electrical impedance tomography
url https://hdl.handle.net/1721.1/138765.2
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