Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer
Abstract The majority of biomedical research is funded by public, governmental, and philanthropic grants. These initiatives often shape the avenues and scope of research across disease areas. However, the prioritization of disease-specific funding is not always reflective of the health and social b...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
Springer Science and Business Media LLC
2022
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| Online Access: | https://hdl.handle.net/1721.1/139849 |
| _version_ | 1826206648233885696 |
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| author | Ramadi, Khalil B. Mehta, Rhea He, David Chao, Sichen Chu, Zen Atun, Rifat Nguyen, Freddy T. |
| author2 | Massachusetts Institute of Technology. School of Engineering |
| author_facet | Massachusetts Institute of Technology. School of Engineering Ramadi, Khalil B. Mehta, Rhea He, David Chao, Sichen Chu, Zen Atun, Rifat Nguyen, Freddy T. |
| author_sort | Ramadi, Khalil B. |
| collection | MIT |
| description | Abstract
The majority of biomedical research is funded by public, governmental, and philanthropic grants. These initiatives often shape the avenues and scope of research across disease areas. However, the prioritization of disease-specific funding is not always reflective of the health and social burden of each disease. We identify a prioritization disparity between lung and breast cancers, whereby lung cancer contributes to a substantially higher socioeconomic cost on society yet receives significantly less funding than breast cancer. Using search engine results and natural language processing (NLP) of Twitter tweets, we show that this disparity correlates with enhanced public awareness and positive sentiment for breast cancer. Interestingly, disease-specific venture activity does not correlate with funding or public opinion. We use outcomes from recent early-stage innovation events focused on lung cancer to highlight the complementary mechanism by which bottom-up “grass-roots” initiatives can identify and tackle under-prioritized conditions. |
| first_indexed | 2024-09-23T13:36:06Z |
| format | Article |
| id | mit-1721.1/139849 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T13:36:06Z |
| publishDate | 2022 |
| publisher | Springer Science and Business Media LLC |
| record_format | dspace |
| spelling | mit-1721.1/1398492024-03-22T20:20:53Z Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer Ramadi, Khalil B. Mehta, Rhea He, David Chao, Sichen Chu, Zen Atun, Rifat Nguyen, Freddy T. Massachusetts Institute of Technology. School of Engineering Sloan School of Management Massachusetts Institute of Technology. Institute for Medical Engineering & Science Abstract The majority of biomedical research is funded by public, governmental, and philanthropic grants. These initiatives often shape the avenues and scope of research across disease areas. However, the prioritization of disease-specific funding is not always reflective of the health and social burden of each disease. We identify a prioritization disparity between lung and breast cancers, whereby lung cancer contributes to a substantially higher socioeconomic cost on society yet receives significantly less funding than breast cancer. Using search engine results and natural language processing (NLP) of Twitter tweets, we show that this disparity correlates with enhanced public awareness and positive sentiment for breast cancer. Interestingly, disease-specific venture activity does not correlate with funding or public opinion. We use outcomes from recent early-stage innovation events focused on lung cancer to highlight the complementary mechanism by which bottom-up “grass-roots” initiatives can identify and tackle under-prioritized conditions. 2022-02-04T16:03:53Z 2022-02-04T16:03:53Z 2022-01-21 Article http://purl.org/eprint/type/JournalArticle 2398-6352 https://hdl.handle.net/1721.1/139849 Ramadi, K.B., Mehta, R., He, D. et al. Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer. npj Digit. Med. 5, 10 (2022) 10.1038/s41746-021-00545-x npj Digital Medicine Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf Springer Science and Business Media LLC Nature |
| spellingShingle | Ramadi, Khalil B. Mehta, Rhea He, David Chao, Sichen Chu, Zen Atun, Rifat Nguyen, Freddy T. Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer |
| title | Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer |
| title_full | Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer |
| title_fullStr | Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer |
| title_full_unstemmed | Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer |
| title_short | Grass-roots entrepreneurship complements traditional top-down innovation in lung and breast cancer |
| title_sort | grass roots entrepreneurship complements traditional top down innovation in lung and breast cancer |
| url | https://hdl.handle.net/1721.1/139849 |
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