Chromatin accessibility informs cell identity: studies in silico, in vitro, and in vivo
Chromatin accessibility provides key regulation in defining cell identity as it exhibits control over the ability of transcription factors and transcriptional machinery to bind to regulatory elements and initiate changes to gene expression. In this thesis I elaborate on the intricate relationships b...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/140060 |