Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz
© 2019 Elsevier Inc. We describe the design and construction of a modular, triple-resonance, fully balanced, DNP-MAS probe based on transmission line technology and its integration into a 500 MHz/330 GHz DNP-NMR spectrometer. A novel quantitative probe design and characterization strategy is develop...
| Main Authors: | , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV
2022
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| Online Access: | https://hdl.handle.net/1721.1/141066 |
| _version_ | 1826188064594067456 |
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| author | Reese, Marcel George, Christy Yang, Chen Jawla, Sudheer Grün, J Tassilo Schwalbe, Harald Redfield, Christina Temkin, Richard J Griffin, Robert G |
| author2 | Massachusetts Institute of Technology. Plasma Science and Fusion Center |
| author_facet | Massachusetts Institute of Technology. Plasma Science and Fusion Center Reese, Marcel George, Christy Yang, Chen Jawla, Sudheer Grün, J Tassilo Schwalbe, Harald Redfield, Christina Temkin, Richard J Griffin, Robert G |
| author_sort | Reese, Marcel |
| collection | MIT |
| description | © 2019 Elsevier Inc. We describe the design and construction of a modular, triple-resonance, fully balanced, DNP-MAS probe based on transmission line technology and its integration into a 500 MHz/330 GHz DNP-NMR spectrometer. A novel quantitative probe design and characterization strategy is developed and employed to achieve optimal sensitivity, RF homogeneity and excellent isolation between channels. The resulting three channel HCN probe has a modular design with each individual, swappable module being equipped with connectorized, transmission line ports. This strategy permits attachment of a mating connector that facilitates accurate impedance measurements at these ports and allows characterization and adjustment (e.g. for balancing or tuning/matching) of each component individually. The RF performance of the probe is excellent; for example, the 13C channel attains a Rabi frequency of 280 kHz for a 3.2 mm rotor. In addition, a frequency tunable 330 GHz gyrotron operating at the second harmonic of the electron cyclotron frequency was developed for DNP applications. Careful alignment of the corrugated waveguide led to minimal loss of the microwave power, and an enhancement factor ε = 180 was achieved for U-13C urea in the glassy matrix at 80 K. We demonstrated the operation of the system with acquisition of multidimensional spectra of cross-linked lysozyme crystals which are insoluble in glycerol-water mixtures used for DNP and samples of RNA. |
| first_indexed | 2024-09-23T07:54:03Z |
| format | Article |
| id | mit-1721.1/141066 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T07:54:03Z |
| publishDate | 2022 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1410662023-03-28T20:12:24Z Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz Reese, Marcel George, Christy Yang, Chen Jawla, Sudheer Grün, J Tassilo Schwalbe, Harald Redfield, Christina Temkin, Richard J Griffin, Robert G Massachusetts Institute of Technology. Plasma Science and Fusion Center Massachusetts Institute of Technology. Department of Physics Francis Bitter Magnet Laboratory (Massachusetts Institute of Technology) Massachusetts Institute of Technology. Department of Chemistry © 2019 Elsevier Inc. We describe the design and construction of a modular, triple-resonance, fully balanced, DNP-MAS probe based on transmission line technology and its integration into a 500 MHz/330 GHz DNP-NMR spectrometer. A novel quantitative probe design and characterization strategy is developed and employed to achieve optimal sensitivity, RF homogeneity and excellent isolation between channels. The resulting three channel HCN probe has a modular design with each individual, swappable module being equipped with connectorized, transmission line ports. This strategy permits attachment of a mating connector that facilitates accurate impedance measurements at these ports and allows characterization and adjustment (e.g. for balancing or tuning/matching) of each component individually. The RF performance of the probe is excellent; for example, the 13C channel attains a Rabi frequency of 280 kHz for a 3.2 mm rotor. In addition, a frequency tunable 330 GHz gyrotron operating at the second harmonic of the electron cyclotron frequency was developed for DNP applications. Careful alignment of the corrugated waveguide led to minimal loss of the microwave power, and an enhancement factor ε = 180 was achieved for U-13C urea in the glassy matrix at 80 K. We demonstrated the operation of the system with acquisition of multidimensional spectra of cross-linked lysozyme crystals which are insoluble in glycerol-water mixtures used for DNP and samples of RNA. 2022-03-08T19:51:24Z 2022-03-08T19:51:24Z 2019 2022-03-08T19:46:30Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/141066 Reese, Marcel, George, Christy, Yang, Chen, Jawla, Sudheer, Grün, J Tassilo et al. 2019. "Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz." Journal of Magnetic Resonance, 307. en 10.1016/J.JMR.2019.106573 Journal of Magnetic Resonance Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV PMC |
| spellingShingle | Reese, Marcel George, Christy Yang, Chen Jawla, Sudheer Grün, J Tassilo Schwalbe, Harald Redfield, Christina Temkin, Richard J Griffin, Robert G Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| title | Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| title_full | Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| title_fullStr | Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| title_full_unstemmed | Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| title_short | Modular, triple-resonance, transmission line DNP MAS probe for 500 MHz/330 GHz |
| title_sort | modular triple resonance transmission line dnp mas probe for 500 mhz 330 ghz |
| url | https://hdl.handle.net/1721.1/141066 |
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