Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer’s β-Amyloid Fibrils Studied Using 19F Solid-State NMR

Binding Sites of a Positron Emission Tomography Imaging Agent in Alzheimer’s β-Amyloid Fibrils Studied Using 19F Solid-State NMR

Amyloid imaging by positron emission tomography (PET) is an important method for diagnosing neurodegenerative disorders such as Alzheimer's disease. Many 11C- and 18F-labeled PET tracers show varying binding capacities, specificities, and affinities for their target proteins. The structural bas...

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Bibliographic Details
Main Authors: Duan, Pu, Chen, Kelly J, Wijegunawardena, Gayani, Dregni, Aurelio J, Wang, Harrison K, Wu, Haifan, Hong, Mei
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/141080

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