Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells

© LL-37 is a secretory peptide that has antimicrobial activity. Ribonuclease 1 (RNase 1) is a secretory enzyme that is not cytotoxic. We find that human LL-37 and human RNase 1 can act synergistically to kill Gram-negative bacterial cells. In the presence of nontoxic concentrations of LL-37, RNase...

Full description

Bibliographic Details
Main Authors: Eller, Chelcie H, Raines, Ronald T
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/141233

Similar Items