Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity
© 2020 The Author(s) Inflammasome activation in dendritic cells (DCs) leads to pyroptosis or hyperactivation. Zhivaki et al. show that in contrast to pyroptotic DCs, hyperactive DCs stimulate durable anti-tumor immunity that eradicates established tumors. These protective responses are intrinsic to...
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Bibliographic Details
| Main Authors: |
Zhivaki, Dania,
Borriello, Francesco,
Chow, Ohn A,
Doran, Benjamin,
Fleming, Ira,
Theisen, Derek J,
Pallis, Paris,
Shalek, Alex K,
Sokol, Caroline L,
Zanoni, Ivan,
Kagan, Jonathan C |
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| Other Authors: |
Massachusetts Institute of Technology. Department of Chemistry |
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| Format: | Article
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| Language: | English |
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| Published: |
Elsevier BV
2022
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| Online Access: | https://hdl.handle.net/1721.1/141288
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