Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

The skin lesion erythema migrans (EM) is an initial sign of the Ixodes tick-transmitted Borreliella spirochetal infection known as Lyme disease. T cells and innate immune cells have previously been shown to predominate the EM lesion and promote the reaction. Despite the established importance of B c...

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Bibliographic Details
Main Authors: Jiang, Ruoyi, Meng, Hailong, Raddassi, Khadir, Fleming, Ira, Hoehn, Kenneth B, Dardick, Kenneth R, Belperron, Alexia A, Montgomery, Ruth R, Shalek, Alex K, Hafler, David A, Kleinstein, Steven H, Bockenstedt, Linda K
Other Authors: Ragon Institute of MGH, MIT and Harvard
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022
Online Access:https://hdl.handle.net/1721.1/141303

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https://hdl.handle.net/1721.1/141303

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