Dual modes of CRISPR-associated transposon homing

Dual modes of CRISPR-associated transposon homing

Tn7-like transposons have co-opted CRISPR systems, including class 1 type I-F, I-B, and class 2 type V-K. Intriguingly, although these CRISPR-associated transposases (CASTs) undergo robust CRISPR RNA (crRNA)-guided transposition, they are almost never found in sites targeted by the crRNAs encoded by...

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Bibliographic Details
Main Authors: Saito, Makoto, Ladha, Alim, Strecker, Jonathan, Faure, Guilhem, Neumann, Edwin, Altae-Tran, Han, Macrae, Rhiannon K., Zhang, Feng
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/142535.2

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