Systems Biology Approaches for Elucidating Early ALS Disease Processes

ALS is a devastating neurodegenerative disorder with no known cure. In this thesis, I describe high-throughput omics characterization of patient-derived induced pluripotent stem cell (iPSC) models. I present analyses aimed at discovering disease pathways and genes associated with ALS using systems b...

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Bibliographic Details
Main Author: Li, Jonathan
Other Authors: Fraenkel, Ernest
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/143216
https://orcid.org/ 0000-0003-0782-2077