Design of Nuclear-Targeting Peptides for Macromolecule Delivery via Machine Learning
The effective design of functional peptide sequences remains a fundamental challenge in biomedicine. For example, cell-penetrating peptides (CPPs) are capable of delivering macromolecular cargo to intracellular targets that are otherwise inaccessible. However, design of novel CPPs with high activity...
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis |
Published: |
Massachusetts Institute of Technology
2022
|
Online Access: | https://hdl.handle.net/1721.1/143244 https://orcid.org/ 0000-0003-0773-5168 |