Design of Nuclear-Targeting Peptides for Macromolecule Delivery via Machine Learning

The effective design of functional peptide sequences remains a fundamental challenge in biomedicine. For example, cell-penetrating peptides (CPPs) are capable of delivering macromolecular cargo to intracellular targets that are otherwise inaccessible. However, design of novel CPPs with high activity...

Full description

Bibliographic Details
Main Author: Schissel, Carly Katherine
Other Authors: Pentelute, Bradley L
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/143244
https://orcid.org/ 0000-0003-0773-5168