Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer

Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer

<jats:p>The tumor microenvironment plays a key role in the pathogenesis of colorectal tumors and contains various cell types including epithelial, immune, and mesenchymal cells. Characterization of the interactions between these cell types is necessary for revealing the complex nature of tumor...

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Bibliographic Details
Main Authors: Vega, Paige N, Nilsson, Avlant, Kumar, Manu P, Niitsu, Hiroaki, Simmons, Alan J, Ro, James, Wang, Jiawei, Chen, Zhengyi, Joughin, Brian A, Li, Wei, McKinley, Eliot T, Liu, Qi, Roland, Joseph T, Washington, M Kay, Coffey, Robert J, Lauffenburger, Douglas A, Lau, Ken S
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Frontiers Media SA 2022
Online Access:https://hdl.handle.net/1721.1/143434

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