Tumor cell nuclei soften during transendothelial migration

During cancer metastasis, tumor cells undergo significant deformation in order to traverse through endothelial cell junctions in the walls of blood vessels. As cells pass through narrow gaps, smaller than the nuclear diameter, the spatial configuration of chromatin must change along with the distrib...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Roberts, Anya B, Zhang, Jitao, Raj Singh, Vijay, Nikolić, Miloš, Moeendarbary, Emad, Kamm, Roger D, So, Peter TC, Scarcelli, Giuliano
Muut tekijät: Massachusetts Institute of Technology. Department of Biological Engineering
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Elsevier BV 2022
Linkit:https://hdl.handle.net/1721.1/143442