Tumor cell nuclei soften during transendothelial migration
During cancer metastasis, tumor cells undergo significant deformation in order to traverse through endothelial cell junctions in the walls of blood vessels. As cells pass through narrow gaps, smaller than the nuclear diameter, the spatial configuration of chromatin must change along with the distrib...
Main Authors: | Roberts, Anya B, Zhang, Jitao, Raj Singh, Vijay, Nikolić, Miloš, Moeendarbary, Emad, Kamm, Roger D, So, Peter TC, Scarcelli, Giuliano |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
|
Online Access: | https://hdl.handle.net/1721.1/143442 |
Similar Items
-
Endothelium and Subendothelial Matrix Mechanics Modulate Cancer Cell Transendothelial Migration
by: Yousef Javanmardi, et al.
Published: (2023-06-01) -
Efficient Transendothelial Migration of Latently HIV-1-Infected Cells
by: Reou Tanabe, et al.
Published: (2021-08-01) -
An agent-based model of leukocyte transendothelial migration during atherogenesis.
by: Rita Bhui, et al.
Published: (2017-05-01) -
Methylene blue modulates transendothelial migration of peripheral blood cells.
by: Isabella Werner, et al.
Published: (2013-01-01) -
Rho GTPase signalling networks in cancer cell transendothelial migration
by: Wessel S Rodenburg, et al.
Published: (2021-10-01)