Evolution of delayed resistance to immunotherapy in a melanoma responder
Despite initial responses1-3, most melanoma patients develop resistance4 to immune checkpoint blockade (ICB). To understand the evolution of resistance, we studied 37 tumor samples over 9 years from a patient with metastatic melanoma with complete clinical response to ICB followed by delayed recurre...
Main Author: | Kellis, Manolis |
---|---|
Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2022
|
Online Access: | https://hdl.handle.net/1721.1/143713 |
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