Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

© 2021, The Author(s), under exclusive licence to Springer Nature America, Inc. Metabolic programming controls immune cell lineages and functions, but little is known about γδ T cell metabolism. Here, we found that γδ T cell subsets making either interferon-γ (IFN-γ) or interleukin (IL)-17 have intr...

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Bibliographic Details
Main Authors: Lopes, Noella, McIntyre, Claire, Martin, Stefania, Raverdeau, Mathilde, Sumaria, Nital, Kohlgruber, Ayano C, Fiala, Gina J, Agudelo, Leandro Z, Dyck, Lydia, Kane, Harry, Douglas, Aaron, Cunningham, Stephen, Prendeville, Hannah, Loftus, Roisin, Carmody, Colleen, Pierre, Philippe, Kellis, Manolis, Brenner, Michael, Argüello, Rafael J, Silva-Santos, Bruno, Pennington, Daniel J, Lynch, Lydia
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/143717

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