Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity
<jats:p>The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificit...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
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American Society for Microbiology
2022
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| Online Access: | https://hdl.handle.net/1721.1/143757 |
| _version_ | 1811082330601684992 |
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| author | Latka, Agnieszka Lemire, Sebastien Grimon, Dennis Dams, Dorien Maciejewska, Barbara Lu, Timothy Drulis-Kawa, Zuzanna Briers, Yves |
| author2 | Massachusetts Institute of Technology. Synthetic Biology Center |
| author_facet | Massachusetts Institute of Technology. Synthetic Biology Center Latka, Agnieszka Lemire, Sebastien Grimon, Dennis Dams, Dorien Maciejewska, Barbara Lu, Timothy Drulis-Kawa, Zuzanna Briers, Yves |
| author_sort | Latka, Agnieszka |
| collection | MIT |
| description | <jats:p>The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.</jats:p> |
| first_indexed | 2024-09-23T12:01:25Z |
| format | Article |
| id | mit-1721.1/143757 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T12:01:25Z |
| publishDate | 2022 |
| publisher | American Society for Microbiology |
| record_format | dspace |
| spelling | mit-1721.1/1437572023-06-26T20:34:35Z Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity Latka, Agnieszka Lemire, Sebastien Grimon, Dennis Dams, Dorien Maciejewska, Barbara Lu, Timothy Drulis-Kawa, Zuzanna Briers, Yves Massachusetts Institute of Technology. Synthetic Biology Center Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Research Laboratory of Electronics Singapore-MIT Alliance in Research and Technology (SMART) <jats:p>The antimicrobial resistance crisis has rekindled interest in bacteriophage therapy. Phages have been studied over a century as therapeutics to treat bacterial infections, but one of the biggest challenges for the use of phages in therapeutic interventions remains their high specificity.</jats:p> 2022-07-15T13:03:29Z 2022-07-15T13:03:29Z 2021 2022-07-15T12:58:14Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/143757 Latka, Agnieszka, Lemire, Sebastien, Grimon, Dennis, Dams, Dorien, Maciejewska, Barbara et al. 2021. "Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity." mBio, 12 (3). en 10.1128/MBIO.00455-21 mBio Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf American Society for Microbiology mBio |
| spellingShingle | Latka, Agnieszka Lemire, Sebastien Grimon, Dennis Dams, Dorien Maciejewska, Barbara Lu, Timothy Drulis-Kawa, Zuzanna Briers, Yves Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity |
| title | Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity |
| title_full | Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity |
| title_fullStr | Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity |
| title_full_unstemmed | Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity |
| title_short | Engineering the Modular Receptor-Binding Proteins of Klebsiella Phages Switches Their Capsule Serotype Specificity |
| title_sort | engineering the modular receptor binding proteins of klebsiella phages switches their capsule serotype specificity |
| url | https://hdl.handle.net/1721.1/143757 |
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