High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions

<jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the hos...

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Main Authors: Lai, Yong, Cui, Liang, Babunovic, Gregory H, Fortune, Sarah M, Doench, John G, Lu, Timothy K
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART)
Format: Article
Language:English
Published: American Society for Microbiology 2022
Online Access:https://hdl.handle.net/1721.1/143758
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author Lai, Yong
Cui, Liang
Babunovic, Gregory H
Fortune, Sarah M
Doench, John G
Lu, Timothy K
author2 Singapore-MIT Alliance in Research and Technology (SMART)
author_facet Singapore-MIT Alliance in Research and Technology (SMART)
Lai, Yong
Cui, Liang
Babunovic, Gregory H
Fortune, Sarah M
Doench, John G
Lu, Timothy K
author_sort Lai, Yong
collection MIT
description <jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the host.</jats:p>
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spelling mit-1721.1/1437582024-03-20T20:25:48Z High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions Lai, Yong Cui, Liang Babunovic, Gregory H Fortune, Sarah M Doench, John G Lu, Timothy K Singapore-MIT Alliance in Research and Technology (SMART) Massachusetts Institute of Technology. Synthetic Biology Center Massachusetts Institute of Technology. Research Laboratory of Electronics Ragon Institute of MGH, MIT and Harvard Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Biological Engineering <jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the host.</jats:p> 2022-07-15T13:06:45Z 2022-07-15T13:06:45Z 2021 2022-07-15T13:02:15Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/143758 Lai, Yong, Cui, Liang, Babunovic, Gregory H, Fortune, Sarah M, Doench, John G et al. 2021. "High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions." mBio, 12 (6). en 10.1128/MBIO.02158-21 mBio Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf American Society for Microbiology mBio
spellingShingle Lai, Yong
Cui, Liang
Babunovic, Gregory H
Fortune, Sarah M
Doench, John G
Lu, Timothy K
High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
title High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
title_full High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
title_fullStr High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
title_full_unstemmed High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
title_short High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
title_sort high throughput crispr screens to dissect macrophage shigella interactions
url https://hdl.handle.net/1721.1/143758
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