High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions
<jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the hos...
Main Authors: | , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2022
|
Online Access: | https://hdl.handle.net/1721.1/143758 |
_version_ | 1826210759247396864 |
---|---|
author | Lai, Yong Cui, Liang Babunovic, Gregory H Fortune, Sarah M Doench, John G Lu, Timothy K |
author2 | Singapore-MIT Alliance in Research and Technology (SMART) |
author_facet | Singapore-MIT Alliance in Research and Technology (SMART) Lai, Yong Cui, Liang Babunovic, Gregory H Fortune, Sarah M Doench, John G Lu, Timothy K |
author_sort | Lai, Yong |
collection | MIT |
description | <jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the host.</jats:p> |
first_indexed | 2024-09-23T14:55:12Z |
format | Article |
id | mit-1721.1/143758 |
institution | Massachusetts Institute of Technology |
language | English |
last_indexed | 2024-09-23T14:55:12Z |
publishDate | 2022 |
publisher | American Society for Microbiology |
record_format | dspace |
spelling | mit-1721.1/1437582024-03-20T20:25:48Z High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions Lai, Yong Cui, Liang Babunovic, Gregory H Fortune, Sarah M Doench, John G Lu, Timothy K Singapore-MIT Alliance in Research and Technology (SMART) Massachusetts Institute of Technology. Synthetic Biology Center Massachusetts Institute of Technology. Research Laboratory of Electronics Ragon Institute of MGH, MIT and Harvard Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Biological Engineering <jats:p>Treatment for shigellosis is becoming increasingly difficult as resistance to antibiotics becomes more prevalent. One way to prevent this significant public health problem from developing into a full-blown crisis is to approach shigellosis intervention from the point of view of the host.</jats:p> 2022-07-15T13:06:45Z 2022-07-15T13:06:45Z 2021 2022-07-15T13:02:15Z Article http://purl.org/eprint/type/JournalArticle https://hdl.handle.net/1721.1/143758 Lai, Yong, Cui, Liang, Babunovic, Gregory H, Fortune, Sarah M, Doench, John G et al. 2021. "High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions." mBio, 12 (6). en 10.1128/MBIO.02158-21 mBio Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf American Society for Microbiology mBio |
spellingShingle | Lai, Yong Cui, Liang Babunovic, Gregory H Fortune, Sarah M Doench, John G Lu, Timothy K High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions |
title | High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions |
title_full | High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions |
title_fullStr | High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions |
title_full_unstemmed | High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions |
title_short | High-Throughput CRISPR Screens To Dissect Macrophage- Shigella Interactions |
title_sort | high throughput crispr screens to dissect macrophage shigella interactions |
url | https://hdl.handle.net/1721.1/143758 |
work_keys_str_mv | AT laiyong highthroughputcrisprscreenstodissectmacrophageshigellainteractions AT cuiliang highthroughputcrisprscreenstodissectmacrophageshigellainteractions AT babunovicgregoryh highthroughputcrisprscreenstodissectmacrophageshigellainteractions AT fortunesarahm highthroughputcrisprscreenstodissectmacrophageshigellainteractions AT doenchjohng highthroughputcrisprscreenstodissectmacrophageshigellainteractions AT lutimothyk highthroughputcrisprscreenstodissectmacrophageshigellainteractions |